15 Science-backed Benefits of Molecular Hydrogen You Need to Know About

We all know antioxidants are great for us. They act as a friendly police force, helping us fight free radicals. Without antioxidants, free radicals can run rampant throughout the body causing damage as they go. We eat more berries, drink tea, and justify our glass of wine each night with the idea the antioxidants in them are what make each of these a healthy choice.

But there’s a new sheriff in town.

Molecular hydrogen or H2 gas is a very small neutrally charged molecule that has the ability to cross cell membranes and the blood-brain barrier. This gives it the unique ability to access DNA and mitochondria within the cell where it has protective action.

Free radicals are uncharged or unstable molecules, which make them highly reactive and extremely likely that they’ll pull apart pieces of other molecules to gain stability. In their search for stability, they can damage your body. Sometimes this can result in chain reactions. Antioxidants are molecules that safely stabilize free radicals and reduce the amount of damage that can be done.

The most common way to consume molecular hydrogen is with a tablet you drop into your water, which releases hydrogen gas. When I first heard about hydrogen water, my eyebrows raised. I was initially skeptical because hydrogen is so abundant, why had we not realized the power of this element before? Turns out we had been missing a very important possibility that has been right under our noses.

Molecular hydrogen has so many wonderful benefits and acts as a powerful antioxidant neutralizing free radicals that contribute to disease progression. I now think it’s a straightforward and easy supplement everyone should add to their day. You simply drop a hydrogen tablet into your cup of water first thing in the morning and drink the effervescence that develops.

I think molecular hydrogen is going to be one of the biggest health and wellness trends in the upcoming years. Fortunately, by reading this, you’re ahead of the game.

1. Hydrogen acts as an antioxidant

Hydrogen gas acts as powerful antioxidant and has been shown to protect cells from even the most cytotoxic reactive oxygen species. Specifically, inhalation of H2 gas has been shown to suppress brain injuries through these effects.

2. Hydrogen supports your body’s antioxidant system

H2 supports your body’s natural antioxidant system by signaling pathways associated with the prevention of disease.

3. Hydrogen is anti-inflammatory

In animal studies, hydrogen gas has been shown to be extremely anti-inflammatory. While we could use more studies on humans to back these initial findings, research on patients with rheumatoid arthritis are extremely promising.

4. Hydrogen may help reduce pain

As mentioned above, the effects of hydrogen on patients with rheumatoid arthritis have shown a significant decrease in pain. This pain relief is due to the reduction in oxidative stress caused by the anti-inflammatory and antioxidant properties of hydrogen gas.

5. Hydrogen protects your muscles

In an animal study, hydrogen water prevented muscle wasting in mice that had muscular dystrophy. Hydrogen also boosted the natural production of glutathione which is often called our master antioxidant. The effects of hydrogen on athletes and exercise is a promising area worth keeping your eye on.

6. Hydrogen can speed up sport-related recovery

Hydrogen water has been shown to reduce muscle fatigue in elite athletes after intense exercise. This is because it reduced lactic acid buildup, which improved muscle function.

7. Hydrogen can help balance the pH of the blood

Hydrogen water has also been shown to have an alkalizing effect in the blood. This is especially beneficial to people who are extremely physically active because extreme exercise can cause metabolic acidosis.

8. Hydrogen affects cell modulation

Hydrogen appears to have effects in the cells that help them maintain homeostasis and healthy modulation. Through healthy gene expression and cellular metabolism, hydrogen positively affects cellular processes on many different levels.

9. Hydrogen is neuroprotective

Hydrogen has been shown to reduce damage to the brain in Parkinson’s patients. It’s also shown to have generally neuroprotective properties due to its ability to fight oxidative stress.

10. Hydrogen is protective against metabolic conditions

Studies have found that hydrogen increases insulin sensitivity, decreases blood sugar, and blood cholesterol levels. These effects make hydrogen up potential therapy for fighting obesity, diabetes, and metabolic syndrome.

11. Hydrogen boosts your mitochondria

Your mitochondria are the powerhouse of your cells, which makes them directly responsible for your energy levels day to day. Clinical studies on hydrogen-rich water have found that it improves mitochondrial function.

12. Hydrogen protects against DNA damage

Hydrogen gas has been shown to significantly protect DNA against radiation damage. It does so by scavenging hydroxyl radical formation.

13. Hydrogen can calm allergic reactions

With allergies on the rise across the world, this is an interesting observation. Studies have found that in animals, hydrogen can sometimes calm allergic reactions. The way hydrogen appears to calm allergic reactions is by modulating cell processes and restoring homeostasis. It seems that hydrogen restores healthy processes throughout the body, which makes it a good idea for just about everyone to consider taking.

14. Hydrogen is protective against cancer

Hydrogen appears to be protective against cancer. At this point, it probably doesn’t surprise you since you know how hydrogen can protect against oxidative stress and damage to the DNA. Hydrogen has also been observed to help reduce side effects of chemotherapy in some patients.

15. Hydrogen protects organs

Hydrogen has been observed to be protective against damage to numerous organs including the brain, pancreas, heart, liver, eyes, and lungs. This is believed to be because of hydrogen’s anti-inflammatory, antiapoptotic, and oxidative stress fighting effects.

As I said before, I think molecular hydrogen is going to be one of the biggest buzzwords in the health industry. Please also share this article with your friends and family because molecular hydrogen might be one of the simplest and additions they can make to their life today that has tremendous benefits.

Resources

  1. Ohsawa I, et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nature Medicine volume 13, pages 688–694 (2007).
  2. Yu J et al. Molecular hydrogen attenuates hypoxia/reoxygenation injury of intrahepatic cholangiocytes by activating Nrf2 expression. Toxicol Lett. 2015 Nov 4;238(3):11-9.
  3. Gharib B, et al. Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation. C R Acad Sci III. 2001 Aug;324(8):719-24.
  4. Ishibashi T, et al. Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study. Med Gas Res. 2012 Oct 2;2(1):27.
  5. Hasegawa S, et al. Molecular hydrogen alleviates motor deficits and muscle degeneration in mdx mice. Redox Rep. 2017 Jan;22(1):26-34. Epub 2016 Feb 15.
  6. Aoki K, et al. Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes. Med Gas Res. 2012 Jul 12;2:12.
  7. Ostojic SM, Stojanovic MD. Hydrogen-rich water affected blood alkalinity in physically active men. Res Sports Med. 2014;22(1):49-60.
  8. Nakai Y, et al. Hepatic oxidoreduction-related genes are upregulated by administration of hydrogen-saturated drinking water. Biosci Biotechnol Biochem. 2011;75(4):774-6. Epub 2011 Apr 22.
  9. Yoritaka A, Abe T, Ohtsuka C, et al. A randomized double-blind multi-center trial of hydrogen water for Parkinson's disease: protocol and baseline characteristics. BMC Neurol. 2016;16:66. Published 2016 May 12.
  10. Kamimura N, et al. Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice. Obesity (Silver Spring). 2011 Jul;19(7):1396-403.
  11. Ito M, et al. Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies. Med Gas Res. 2011 Oct 3;1(1):24.
  12. Abou-Hamdan M, et al. Molecular hydrogen attenuates radiation-induced nucleobase damage to DNA in aerated aqueous solutions. Int J Radiat Biol. 2016 Sep;92(9):536-41.
  13. Itoh T, et al. Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells. Biochem Biophys Res Commun. 2009 Nov 27;389(4):651-6.
  14. Ohta S. Recent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications. Curr Pharm Des. 2011;17(22):2241-52.
  15. Ge L, Yang M, Yang NN, Yin XX, Song WG. Molecular hydrogen: a preventive and therapeutic medical gas for various diseases. Oncotarget. 2017;8(60):102653-102673. Published 2017 Sep 21.

15 Science-backed Benefits of Molecular Hydrogen You Need to Know About originally published on Dr. Jill Carnahan's website, October 14, 2018.

About the Author

Jill Carnahan

Jill Carnahan, M.D., A.B.F.M., A.B.I.H.M., I.F.M.C.P., uses functional medicine to help people find the answers to the cause of their illness and the nutritional and biochemical imbalances that may be making them feel ill. Functional medicine is personalized medicine that deals with root cause of disease instead of just treating symptoms.